The Coahoma County Detention Facility is located at 1 Justice Drive, Clarksdale, MS. and is the central holding facility for criminals in the county. All prisoners from the municipal police departments as well as the Coahoma County Sheriff's Department are housed in the Coahoma County Detention Facility.

The present facility was constructed in 2020 and can house a maximum of 200 inmates. Felony prisoners as well as misdemeanor prisoners are held in this facility.

The mission of the Coahoma County detention facility is to provide professional services for Coahoma County while enforcing the law in a fair and impartial manner recognizing the statutory and judicial limitations and constitutional rights of all persons.